Compromised humoral functional evolution tracks with SARS-CoV-2 mortalityAnalyses of the functional humoral trajectories associated with the resolution of SARS-CoV-2 infection find that in spite of equivalent IgM and IgA immunity to the virus across all levels of disease severity, survival and recovery is linked to early class switching to IgG and the ability to leverage Fcγ-receptors targeting the spike protein.Analyses of the functional humoral trajectories associated with the resolution of SARS-CoV-2 infection find that in spite of equivalent IgM and IgA immunity to the virus across all levels of disease severity, survival and recovery is linked to early class switching to IgG and the ability to leverage Fcγ-receptors targeting the spike protein.Tomer Zohar, Carolin Loos, Stephanie Fischinger, Caroline Atyeo, Chuangqi Wang, Matthew D. Slein, John Burke, Jingyou Yu, Jared Feldman, Blake Marie Hauser, Tim Caradonna, Aaron Schmidt, Yongfei Cai, Hendrik Streeck, Edward T. Ryan, Dan H. Barouch, Richelle C. Charles, Douglas Lauffenburger, Galit Alterhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2931459-8%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignNovember 4, 2020

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