Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder CancerSingle-cell RNA and paired T cell receptor sequencing highlights enrichment of cytotoxic CD4+ T cells rather than CD8+ T cells in human bladder cancer. These CD4+ T cells are capable of killing autologous tumor cells and are subjected to inhibition by Tregs.Single-cell RNA and paired T cell receptor sequencing highlights enrichment of cytotoxic CD4+ T cells rather than CD8+ T cells in human bladder cancer. These CD4+ T cells are capable of killing autologous tumor cells and are subjected to inhibition by Tregs.David Y. Oh, Serena S. Kwek, Siddharth S. Raju, Tony Li, Elizabeth McCarthy, Eric Chow, Dvir Aran, Arielle Ilano, Chien-Chun Steven Pai, Chiara Rancan, Kathryn Allaire, Arun Burra, Yang Sun, Matthew H. Spitzer, Serghei Mangul, Sima Porten, Maxwell V. Meng, Terence W. Friedlander, Chun Jimmie Ye, Lawrence Fonghttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2930612-7%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJune 4, 2020

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