Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy StrainsStructural and mass spectrometry-based proteomics of tau filaments, including their posttranslational modifications, from corticobasal degeneration and Alzheimer’s disease point to how cross-talk between posttranslational modifications influences fibril structure, contributing to the structural diversity of tauopathy strains.Structural and mass spectrometry-based proteomics of tau filaments, including their posttranslational modifications, from corticobasal degeneration and Alzheimer’s disease point to how cross-talk between posttranslational modifications influences fibril structure, contributing to the structural diversity of tauopathy strains.Tamta Arakhamia, Christina E. Lee, Yari Carlomagno, Duc M. Duong, Sean R. Kundinger, Kevin Wang, Dewight Williams, Michael DeTure, Dennis W. Dickson, Casey N. Cook, Nicholas T. Seyfried, Leonard Petrucelli, Anthony W.P. Fitzpatrickhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2930108-2%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 7, 2020

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