Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting

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Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by BoostingA clonal dynamics analysis of the transition between primary and recall B cell responses in mice reveals a clonality bottleneck that constricts the breadth of the secondary antibody response and limits reentry of previously matured B cells into secondary germinal centers.A clonal dynamics analysis of the transition between primary and recall B cell responses in mice reveals a clonality bottleneck that constricts the breadth of the secondary antibody response and limits reentry of previously matured B cells into secondary germinal centers.Luka Mesin, Ariën Schiepers, Jonatan Ersching, Alexandru Barbulescu, Cecília B. Cavazzoni, Alessandro Angelini, Takaharu Okada, Tomohiro Kurosaki, Gabriel D. Victorahttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2819%2931317-0%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 20, 2019

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